This review describes the endeavors that led to the total synthesis of a novel class of antibiotic compounds: the crocacins A-D. Other aspects such as isolation, structural elucidation as well as the biological activities are also presented.

A preparação de uma série de beta-enamino cetonas e ésteres empregando a metodologia de reações em suporte sólido associada à irradiação de microondas é descrita. As reações dos compostos beta-dicarbonílicos cíclicos, acíclicos e alfa-cloro-substituídos, frente a aminas primárias ou aos acetatos de amônio correspondentes, foram efetuadas usando K-10 como suporte sólido e forno de microondas doméstico como fonte de irradiação, obtendo-se os beta-enamino compostos com ótimos rendimentos.

The preparation of beta-enamino ketones and esters using the methodology of the reactions on solid support coupled with microwave irradiation is described. The reaction of cyclic, acyclic and alpha-chloro-substituted beta-dicarbonyl compounds with amines or their corresponding ammonium acetates was carried out using K-10 as solid support and a domestic microwave oven as the radiation source to give beta-enamino carbonylic compounds in good yields.